Odds makers at BetUS currently have the Bearcats listed as 4-point favorites versus the Cardinals, while the game's total is sitting at 47½.
Kazeem Alli caught the winning touchdown in overtime in Week 11, as Cincinnati got by West Virginia 26-23. The 49 points made it OVER the posted total of 45.5.
Tony Pike completed 15-of-30 for 165 yards with one TD, and rushed for a touchdown in the win.
Hunter Cantwell completed 15-of-28 pass attempts for 164 yards, one touchdown and one interception as Louisville lost 41-7 to Pittsburgh in Week 11.
The Cardinals did not cover the 6.5-point spread, while the combined score played UNDER the day's posted total of 52.5.
A few trends to consider:
Cincinnati is 6-1 SU in its last 7 games
Cincinnati is 9-3 SU in its last 12 games on the road
Cincinnati is 1-4 ATS in its last 5 games when playing Louisville
Cincinnati is 1-4 SU in its last 5 games when playing on the road against Louisville
Louisville is 5-0 SU in its last 5 games when playing Cincinnati
Louisville is 21-4 SU in its last 25 games at home
Louisville is 4-1 SU in its last 5 games when playing at home against Cincinnati
Louisville is 4-1 ATS in its last 5 games when playing Cincinnati
Next up:
Cincinnati home to Pittsburgh, Saturday, November 22
Louisville home to West Virginia, Saturday, November 22