New York Giants (-6) @ Tampa Bay Buccaneers
Sunday, September 27, 1:00 p.m. ET
Eli Manning may have taken his game to a new level in leading the Giants to a come-from-behind victory against the Cowboys last week. Lacking a true No. 1 receiver, he’s made the most of Steve Smith and Mario Manningham and is suddenly developing a nice rapport with them. After handling Washington and Dallas’ solid defenses, he should have no trouble picking apart the disappointing Tampa unit. Byron Leftwich and the Bucs offense have been better than expected but they aren’t prepared for the swarming Giants front seven. It could get ugly.
Betting services recommend: Giants -6
Washington Redskins (-6.5) @ Detroit Lions
Sunday, September 27, 1:00 p.m. ET
OK, folks – here’s the first big upset pick of the season. Think about it. The Redskins are favored by a touchdown on the road when they barely got by the Rams last week, scraping by 9-7. Now, they face a Lions team with much better offensive weapons that St. Louis. Matt Stafford may have the time he needs to avoid getting flustered; the Redskins haven’t gotten to the quarterback, recording only two sacks through two games. Don’t be surprised if Calvin Johnson goes off. Even if you don’t think the Lions will win, don’t you think they can beat a 6.5 spread at home against an anemic offense?
Betting services recommend: Lions +6.5
San Francisco 49ers @ Minnesota Vikings (-6.5)
Sunday, September 27, 1:00 p.m. ET
Time to really find out if the 49ers’ NFL odds are legit. Frank Gore carved up Seattle, but can he handle the Williams Wall? If the Vikings shut him down, San Fran will have to throw the ball. Shaun Hill seems more like a caretaker despite his good win-loss record; I don’t think he can carry the 49ers when he needs to. The 49er “D” has been strong but facing Adrian Peterson is a major upgrade from Tim Hightower and Julius Jones.
Betting services recommend: Vikings -6.5