The Catalans will also rivals Dinamo Kiev Ukrainian and Russian Rubin Kazan, but the big draw will see the elastic Zlatan Ibrahimovic with Barca facing his former teammates interest and the same thing in reverse in the case of Cameroon's Samuel Eto 'o, former Barca and now at Inter which will see the faces with Messi, Xavi and Iniesta, their former owners in attendance.
In addition, for Mourinho, coach of Inter, return to the Nou Camp will be special, after having taken his first steps as an assistant coach there.
"To all the team to beat, we are the European champions," said Rafael Yuste, vice president of FC Barcelona.
Also, when Real Madrid will intersect with the great expectation Milan at San Siro will see Kaka, champion in 2007 as brand reinforcement rossonero and Real Madrid, putting passes goal against his former teammates of Milan, who sold the Brazilian to the White House by about 65 million.
But there will be a duel between the two teams with more European titles. Real Madrid and home ranks among total 16 'eared' (9 Real Milan and 7).
Real, after beginning a new era 'galactic' Cristiano Ronaldo, Kaka and Karim Benzema, measured their stripes against rossonero Brazilians Ronaldinho, the former Barça, and Duck.
In the group C, Spanish and Italians are big favorites, but could struggle against the reinforced French Marseille Didier Deschamps. The Swiss Zurich seems destined to play a supporting role.
The top two from each key advance to the knockout stage, while third-placed passes to the Europa League. The fourth placed team is eliminated.
For his part, Spanish Sevilla had a favorable draw, the rivals have not much history in Champions: Glasgow Rangers, Stuttgart German and Romanian Unirea Urziceni, inside the key G.
"The truth is that we are happy, because there are many groups more difficult. We are very pleased with the draw," said Jose Castro, vice president of the Andalusian team.
A little more difficult group but with good chances of advancing to the knockout is Atletico Madrid, who in your area D clash with Chelsea English, Portuguese and Oporto Apoel of Cyprus.
The other major British can feel happy about the fate that lie Monaco hype.
Manchester United, champions of the Champions in 2008 and finalist in 2009, is the favorite in Group B, against teams well below their economic potential and football.
Russian CSKA Moscow, Besiktas Turkish and Wolfsburg, but debutant German champions in the tournament, surely fight for the second ticket.
In the E, Liverpool's Rafa Benitez will face a candidate for the French Lyon, host of the tournament eternal lineage but not to go to the end, Fiorentina of Italy, who arrived in this instance surpassing the previous round with difficulty against Sporting Portugal and the modest Hungarian Debrecen.
For its part, Arsenal's Cesc Fabregas is easy on paper against the Netherlands champion in low AZ Alkmaar, Olympiakos Greek and weak Belgian Standard Liege in group H.
More entertaining fight and announced the group A. Bordeaux, French champion, will fight to give the giants Bayern Munich and Juventus, with the arrival of Fabio Cannavaro and Felipe Melo, among others, will be thrown everything in the Champions League. Maccabi Haifa will be almost a 'guest' of luxury.